Champions League holders Liverpool were beaten 1-0 away to Atletico Madrid in their last-16 first leg.
Spain midfielder Saul Niguez struck the only goal of the game in the fourth minute by bundling into the net from close range following a corner.
Elsewhere, a Gabriel Jesus header and a penalty from Kevin De Bruyne sealed a thrilling 2-1 comeback win for Manchester City at Real Madrid, who had captain Sergio Ramos sent off in the first leg of their Champions League last-16 tie.
Dortmund 2-1 PSG
Atalanta 4-1 Valencia
Tottenham 0-1 Leipzig
Chelsea 0-3 Bayern Munich
Napoli 1-1 Barcelona
Lyon 1-0 Juventus